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UpStream Bio Inc.

6.48

-0.0700-1.07%

Post-market: 6.12-0.3600-5.56%18:38 EDT

Volume:515.60K

Turnover:3.36M

Market Cap:354.92M

PE:-2.25

High:6.98

Open:6.62

Low:6.41

Close:6.55

52wk High:33.68

52wk Low:5.85

Shares:54.77M

Float Shares:46.68M

Volume Ratio:1.00

T/O Rate:1.10%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-2.8758

EPS(LYR):-2.6636

ROE:-46.05%

ROA:-30.28%

PB:1.31

PE(LYR):-2.43

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Overview Company News Filings

Top Executive Makes Strategic Move With Upstream Bio Stock

Upstream Bio presents new responder analyses from VIBRANT trial of verekitug

Upstream Bio says Phase 2 VIBRANT trial shows verekitug improves nasal polyp score in about 80% of CRSwNP patients

Upstream Bio Presents New Responder Analyses Demonstrating Clinically Meaningful Improvements in Crswnp in Significant Majority of Participants Treated With Verekitug in the Phase 2 Vibrant Trial at Eaaci 2026

THOMSON REUTERS

Upstream Bio Inc : JP Morgan Cuts to Neutral From Overweight; Cuts Target Price to $8 From $35

THOMSON REUTERS

Upstream Bio Shareholders Elect Directors, Ratify 2026 Auditor

Upstream Bio shareholders elect Fleming, Ratcliffe as Class II directors

Upstream Bio to Showcase Additional Efficacy Data From the Phase 2 Vibrant Trial of Verekitug in Crswnp in Oral Session at Eaaci 2026

THOMSON REUTERS

Upstream Bio Initiated at Buy by HC Wainwright & Co.

Upstream Bio CEO to join Goldman Sachs Global Healthcare Conference fireside chat

Upstream Bio initiated with a Buy at H.C. Wainwright

Upstream Bio, Inc. : H.c. Wainwright Initiates Coverage With Buy Rating

THOMSON REUTERS

Analysts’ Top Healthcare Picks: Upstream Bio, Inc. (UPB), Plus Therapeutics (PSTV)

Upstream Bio presents data from Phase 2 VIBRANT trial of verekitug

Upstream Bio says Phase 2 trial shows verekitug improves asthma control in CRSwNP patients

Upstream Bio Presents New Data From Phase 2 Vibrant Trial of Verekitug Demonstrating Improvement in Asthma Symptom Control in Participants With Crswnp and Comorbid Asthma at the ATS 2026 International Conference

THOMSON REUTERS

LifeSci Capital Reaffirms Their Buy Rating on Upstream Bio, Inc. (UPB)

Upstream Bio releases corporate deck on verekitug Phase 3 plans for severe asthma, CRSwNP

Analysts Offer Insights on Healthcare Companies: Icecure Medical (ICCM) and Upstream Bio, Inc. (UPB)

Analysts Have Conflicting Sentiments on These Healthcare Companies: Bolt Biotherapeutics (BOLT) and Upstream Bio, Inc. (UPB)

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Upstream Bio, Inc. held its 2026 Annual Meeting of Stockholders on June 9, 202...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/company-announcements/upstream-bio-shareholders-elect-directors-ratify-2026-auditor?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/company-announcements/upstream-bio-shareholders-elect-directors-ratify-2026-auditor?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","UPB"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2642447511","title":"Upstream Bio shareholders elect Fleming, Ratcliffe as Class II directors","url":"https://stock-news.laohu8.com/highlight/detail?id=2642447511","media":"Reuters","labels":["executive"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2642447511?lang=en_us&edition=fundamental","pubTime":"2026-06-11 04:06","pubTimestamp":1781121973,"startTime":"0","endTime":"0","summary":"Upstream Bio held its annual shareholder meeting on June 9, 2026.Shareholders backed the selection of H. 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Upstream Bio Inc. published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on June 10, 2026, and is solely responsible for the information contained therein.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260610:nNDL5ThXcp:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","UPB"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2641486542","title":"Upstream Bio to Showcase Additional Efficacy Data From the Phase 2 Vibrant Trial of Verekitug in Crswnp in Oral Session at Eaaci 2026","url":"https://stock-news.laohu8.com/highlight/detail?id=2641486542","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2641486542?lang=en_us&edition=fundamental","pubTime":"2026-06-08 19:00","pubTimestamp":1780916400,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260608:nTUAXTDQV:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","UPB"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2640490123","title":"Upstream Bio Initiated at Buy by HC Wainwright & Co.","url":"https://stock-news.laohu8.com/highlight/detail?id=2640490123","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2640490123?lang=en_us&edition=fundamental","pubTime":"2026-06-03 20:12","pubTimestamp":1780488720,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/UPB/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  June 03, 2026 08:12 ET (12:12 GMT)","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","UPB"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2640090643","title":"Upstream Bio CEO to join Goldman Sachs Global Healthcare Conference fireside chat","url":"https://stock-news.laohu8.com/highlight/detail?id=2640090643","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2640090643?lang=en_us&edition=fundamental","pubTime":"2026-06-03 19:05","pubTimestamp":1780484716,"startTime":"0","endTime":"0","summary":"Upstream Bio CEO Rand Sutherland will join a fireside chat at the Goldman Sachs 47th Annual Global Healthcare Conference on June 10, 2026.The session is scheduled for 10:40 a.m. ET.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260603:nNDL5slpyr:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU1668664300.SGD","LU2237443978.SGD","IE00BN0W2V16.EUR","LU2237443622.USD","BK4585","LU0061475181.USD","LU2210150020.SGD","LU2750360641.GBP","IE0034235188.USD","BK4516","LU0106831901.USD","GS","LU2237443382.USD","BK4588","LU0742534661.SGD","SG9999014039.USD","LU2265009873.SGD","NDAQ","LU1868836591.USD","IE00B64PRP62.GBP","LU0868494617.USD","LU1791807156.HKD","LU2471134796.USD","IE00BGHQF748.EUR","LU0096364046.USD","LU1894683348.USD","IE00BN0W2W23.USD","LU0868494708.USD","LU2471134952.CNY","LU0942090050.USD","UPB","LU0048573561.USD","IE00BSNM7G36.USD","LU0251131958.USD","LU2237443895.HKD","LU1868837136.USD","LU0251142724.SGD","LU1868836914.USD","SG9999014021.USD","LU1868837300.USD","LU0345770308.USD","LU2095319765.USD","LU2471134879.HKD","BK4533","LU0345770993.USD","GSX","IE0002270589.USD","IE0004086264.USD","LU1894683264.USD","IE00B3QW5Z07.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2640903722","title":"Upstream Bio initiated with a Buy at H.C. 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Wainwright analyst Matthew Caufield initiated coverage of Upstream Bio (UPB) with a Buy rating and $36 price target The company’s lead biologi...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/upstream-bio-initiated-with-a-buy-at-h-c-wainwright-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/upstream-bio-initiated-with-a-buy-at-h-c-wainwright-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","UPB"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2640903689","title":"Upstream Bio, Inc. : H.c. 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Bio presents data from Phase 2 VIBRANT trial of verekitug","url":"https://stock-news.laohu8.com/highlight/detail?id=2636775850","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2636775850?lang=en_us&edition=fundamental","pubTime":"2026-05-18 23:35","pubTimestamp":1779118526,"startTime":"0","endTime":"0","summary":"Upstream Bio (UPB) presented new data from the Phase 2 VIBRANT trial evaluating verekitug in participants with chronic rhinosinusitis with nasal 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patients","url":"https://stock-news.laohu8.com/highlight/detail?id=2636720160","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2636720160?lang=en_us&edition=fundamental","pubTime":"2026-05-18 23:30","pubTimestamp":1779118224,"startTime":"0","endTime":"0","summary":"Upstream Bio presented new Phase 2 VIBRANT trial data at the ATS 2026 International Conference on verekitug in adults with chronic rhinosinusitis with nasal polyps, including patients with comorbid asthma.The analyses showed improved asthma symptom control in patients with comorbid asthma, alongside consistent reductions in nasal polyp burden and sinonasal symptoms versus placebo.Verekitug also lowered the need for rescue systemic steroids or sinus surgery in the comorbid asthma subgroup.A separate post hoc analysis indicated rapid, sustained reductions in type 2 inflammatory biomarkers in blood and nasal secretions, supporting the drug’s proposed mechanism in airway 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Dellorusso covers the...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/lifesci-capital-reaffirms-their-buy-rating-on-upstream-bio-inc-upb-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/lifesci-capital-reaffirms-their-buy-rating-on-upstream-bio-inc-upb-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["UPB"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2635730156","title":"Upstream Bio releases corporate deck on verekitug Phase 3 plans for severe asthma, CRSwNP","url":"https://stock-news.laohu8.com/highlight/detail?id=2635730156","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2635730156?lang=en_us&edition=fundamental","pubTime":"2026-05-14 03:39","pubTimestamp":1778701185,"startTime":"0","endTime":"0","summary":"Upstream Bio outlined Phase 3 plans for verekitug in severe asthma, chronic rhinosinusitis with nasal polyps, targeting single quarterly at-home injection dosing.FDA engagement slated for mid-2026; Phase 3 trials in severe asthma, chronic rhinosinusitis with nasal polyps targeted to start in Q1 2027.Phase 2 severe asthma data highlighted 56% reduction in annualized asthma exacerbation rate versus placebo for 100 mg every 12 weeks; lung function improved 122 mL; FeNO fell 20.4 ppb.Phase 2 chronic rhinosinusitis with nasal polyps data showed nasal polyp score reduction of 1.8 versus placebo; nasal congestion score improved 0.8; need for surgery or systemic steroids reduced 76%.Phase 2 COPD trial VENTURE enrollment capped; data expected in H2 2027; existing capital expected to fund planned operations through 2027.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-g","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260513:nNDL3fXJz6:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["UPB","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2635073422","title":"Analysts Offer Insights on Healthcare Companies: Icecure Medical (ICCM) and Upstream Bio, Inc. 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